完整的透化肌細胞測試系統
溫控8孔浴板(尺寸從400μL到1900μL)
大電池安裝區域和電動XYZ微定位平臺,帶電腦控制
控制和測量力,長度和肌節間距(可選900B / 901C)
可與Aurora Scientific 900B / 901C Sarcomere長度軟件(VSL / HVSL)集成
簡單安裝到倒置顯微鏡
測量力-pCA,kTR,剛度,長度 - 張力和力 - 速度關系
包括用于測量細胞深度的可選光學棱鏡
參考文獻:
K?tter, Sebastian et al. “Human myocytes are protected from titin aggregation-induced stiffening by small heat shock proteins.” The Journal of Cell Biology 204.2 (2014): 187-202.
Alegre-Cebollada, Jorge et al. “S-glutathionylation of cryptic cysteines enhances titin elasticity by blocking protein folding.” Cell 156.6 (2014): 1235-1246.
Hamdani, Nazha et al. “Deranged myofilament phosphorylation and function in experimental heart failure with preserved ejection fraction.” Cardiovascular Research 97.3 (2013): 464-471.
Chung, Eunhee and Gary M. Diffee. “Effect of aging on power output properties in rat skinned cardiac myocytes.” The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 66.12 (2011): 1267-1273.
Horiguchi, Hiroshi et al. “Fabrication and evaluation of reconstructed cardiac tissue and its application to bio-actuated microdevices.” IEEE Transactions on NanoBioscience 8.4 (2009): 349-355.