完整的測試系統,帶有用于小完整肌肉的集成浴裝置
溫控浴板(尺寸從400μL到1900μL)
控制和測量力和長度
兼容標準和倒置顯微鏡
可以與Aurora Scientific 900B Sarcomere長度軟件(HVSL / VSL)集成
分辨率低至0.01μN
力范圍從0.5mN到1000mN
參考文獻:
Norden, Diana M. et al. “Tumor growth increases neuroinflammation, fatigue and depressive-like behavior prior to alterations in muscle function.” Brain, Behavior, and Immunity
Tangney, Jared R. et al. “Timing and magnitude of systolic stretch affect myofilament activation and mechanical work.” American Journal of Physiology-Heart and Circulatory Physiology
Gharanei, Mayel. “Investigation into the cardiotoxic effects of doxorubicin on contractile function and the protection afforded by cyclosporin A using the work-loop assay.” Toxicology in Vitro 28 (2014): 722-731.
Zuo, Li et al. “Low Po2 conditions induce reactive oxygen species formation during contractions in single skeletal muscle fibers.” American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
de Lange, Willem J. et al. “Ablation of cardiac myosin-binding protein-C accelerates contractile kinetics in engineered cardiac tissue.” Journal of General Physiology 141.1 (2013): 73-84.
Tangney, Jared R. “Effects of alterations in sarcomere structure and prestretch timing on cardiac muscle mechanics.” MSc Thesis. University of California San Diego (2012): 1-120.
Zuo, Li, Leonardo Nogueira, and Michael C. Hogan. “Reactive oxygen species formation during tetanic contractions in single isolated Xenopus myofibers.” Journal of Applied Physiology
Rhim, Caroline et al. “Effect of MicroRNA Modulation on Bioartificial Muscle Function.” Tissue Engineering: Part A 16.12 (2010): 3589-3597.